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Which is generic metformin or Glucophage? Metformin (Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet) is a medication prescribed to treat type 2 diabetes and the prevention of type 2 diabetes in patients who are at risk for type 2 diabetes. Side effects of metformin include loss of appetite, bloating, heartburn, gas, nausea, and vomiting.