п»їWeek 1 NFL picks, predictions.
NFL picks and predictions are difficult enough in Week 1 of a given season when we know so little about how offseason roster changes will manifest on the field. Now we're picking NFL games to open a season defined by changes amid the COVID-19 pandemic. Welcome to 2020.
Only two of the 16 games on the Week 1 NFL schedule will feature fans in the stands, as the Chiefs and Jaguars will allow a small percentage of their stadiums' capacities to be filled. So the typical home-field advantage attached to the odds for each game is not as much of a factor.
However, team travel for away games during the coronavirus pandemic is extra stressful, so the teams scheduled to make lengthy trips in Week 1 will be the first to deal with the NFL's extensive health and safety protocols for teams on the road.
Per tradition, the Week 1 NFL schedule begins with the defending Super Bowl champions вЂ” this year the Chiefs вЂ” hosting the Thursday night season-opener, and it ends with a "Monday Night Football" doubleheader.
Here are our Week 1 NFL picks straight up, all the way through that pair of Monday night games.

NFL odds, picks, predictions for Week 1, 2020: Advanced computer model loving Bears, 49ers.
SportsLine's computer model simulated every Week 1 NFL game 10,000 times with surprising results.
NFL odds are on the move as kickoffs approach. In Atlanta, the Falcons are one-point favorites over the Seahawks in the latest NFL spreads from William Hill after opening as one-point underdogs. In Carolina, the visiting Raiders opened as 1.5-point favorites, but the line has since doubled to a field goal. Wide receiver Kenny Golladay (hamstring) is inactive for the Lions, who are still 2.5-point favorites over the NFC North rival Bears in the latest NFL betting lines, up a point from the opener.
On Sunday Night Football, the Cowboys vs. Rams line opened at Dallas -2.5, but betting on L.A. has reduced the spread to -2. All of the Week 1 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 1 NFL picks now.
The SportsLine Projection Model simulates every NFL game 10,000 times and is up over $7,000 for $100 players on its top-rated NFL picks since its inception five years ago.
It also enters the 2020 NFL season on an incredible 96-65 roll on top-rated NFL picks that dates back to the 2017 season. The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.
Now, it has examined the latest Week 1 NFL odds and lines, simulated every snap, and its predictions are in. Head to SportsLine now to see them all.
Top NFL predictions for Week 1.
The Bears struggled offensively, but ranked fourth in the league in scoring defense in 2019 (18.6) in 2019. Chicago is also 5-2-1 against the spread in its last eight meetings against Detroit and on a 9-4 run against the spread versus NFC North foes. SportsLine's model says Chicago covers in over 50 percent of simulations, while the under (42) also brings plenty of value because that hits well over 60 percent of the time.
Another one of the Week 1 NFL picks from the model: The 49ers (-7) cover as home favorites against the Cardinals. Kyler Murray and the Cardinals look prepared to take a step forward in Year Two under Kliff Kingsbury, while the offseason addition of DeAndre Hopkins certainly adds to the allure. However, the 49ers' defense is simply too strong and San Francisco's rushing attack is a perfect compliment.
The 49ers ranked second in the NFL in total defense in 2019 and first against the pass. They allowed just 4.8 net yards per pass attempt thanks to the top defensive front in the league and an experienced and capable secondary led by Richard Sherman.
SportsLine's model predicts that Murray is sacked four times and the 49ers force two turnovers. San Francisco covers in well over 50 percent of simulations, while the under (48) also hits over half the time.
How to make Week 1 NFL picks.
The model also has a strong pick for Tom Brady's debut with the Buccaneers against the Saints, and is calling for a favored Super Bowl contender to go down hard in an upset this week. You can only get every pick for every game at SportsLine.
What NFL picks can you make with confidence in Week 1? And which Super Bowl contender goes down hard? Check out the latest NFL odds below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that is up over $7,000 on its top-rated NFL picks.

NFL picks, predictions for Week 1: Steelers handle Giants; 49ers, Ravens upset by Cardinals, Browns.
NFL picks and predictions are difficult enough in Week 1 of a given season when we know so little about how offseason roster changes will manifest on the field. Now we're picking NFL games to open a season defined by changes amid the COVID-19 pandemic. Welcome to 2020.
Only two of the 16 games on the Week 1 NFL schedule will feature fans in the stands, as the Chiefs and Jaguars will allow a small percentage of their stadiums' capacities to be filled. So the typical home-field advantage attached to the odds for each game is not as much of a factor.
However, team travel for away games during the coronavirus pandemic is extra stressful, so the teams scheduled to make lengthy trips in Week 1 will be the first to deal with the NFL's extensive health and safety protocols for teams on the road.
Per tradition, the Week 1 NFL schedule begins with the defending Super Bowl champions вЂ” this year the Chiefs вЂ” hosting the Thursday night season-opener, and it ends with a "Monday Night Football" doubleheader.
Here are our Week 1 NFL picks straight up, all the way through that pair of Monday night games.
NFL picks, predictions for Week 1.
Houston Texans at Kansas City Chiefs (-9 1/2)
Thursday, 8:20 p.m. ET, NBC.
This won't be the party the Chiefs hoped it would be with only about 20 percent of Arrowhead Stadium's capacity filled with Kansas City faithful. But it should still come with the desired result. The Chiefs lost almost nothing from their Super Bowl-winning roster, and while the Texans remain competive on the strength of Deshaun Watson's brilliance, they still don't stack up. There's a reason we like Patrick Mahomes' crew to repeat as champions.
Pick : Chiefs 30, Texans 17.
Green Bay Packers at Minnesota Vikings (-2 1/2)
Sunday, 1 p.m. ET, Fox.
Many were bothered by how the Packers handled their roster in the offseason. But even with Jordan Love in the picture, as long as Aaron Rodgers is playing quarterback, Green Bay's offense will be a problem for opposing teams. Of course, the Vikings are uniquely equipped to give the Packers issues, too. This one will be as close as the odds suggest.
Pick : Packers 27, Vikings 23.
Miami Dolphins at New England Patriots (-6)
Sunday, 1 p.m. ET, CBS.
This would be a lot more fun if Tua Tagovailoa were starting over Ryan Fitzpatrick for the Dolphins, but we'll take what we can get with Cam Newton starting for the Patriots in their first post-Tom Brady era game. New England hasn't had much time to integrate the QB who was signed just before training camp, which would be an issue for anybody but Bill Belichick and Josh McDaniels.
Pick : Patriots 24, Dolphins 13.
Philadelphia Eagles (-6 1/2) at Washington Football Team.
Sunday, 1 p.m. ET, Fox.
The Week 1 NFL schedule was finalized so long ago that one of these teams went by a different name when it was announced. Washington has been fortunate to have new coach Ron Rivera guide the team through a turbulent offseason, but he won't be able to steer his players to many wins in 2020. The slate begins with the NFC East rival that won the division last year and has a solid chance to repeat.
Pick : Eagles 28, Washington 17.
Seattle Seahawks (-2) at Atlanta Falcons.
Sunday, 1 p.m. ET, Fox.
This is a tough spot for the Seahawks, the team we like to win the NFC this season. It's a long road trip for an early kickoff, but at least Seattle has the cushion of the offseason rather than having to deal with such a challenge in the middle of their schedule. The Falcons are a tough team to read going into Week 1. We feel more confident about what we'll get from Russell Wilson and Co.
Pick : Seahawks 30, Falcons 20.
Cleveland Browns at Baltimore Ravens (-8 1/2)
Sunday, 1 p.m. ET, CBS.
Weird, inexplicable upsets in Week 1 are relatively common, especially when division opponents collide to begin a season. Which makes this a dangerous game for the Ravens, who speaking of inexplicable upsets got blown out by the Browns as one of their two regular-season losses last year. Cleveland has new, offensive-minded coach Kevin Stefanski and hopes of contending in the AFC North (for real this time). This game is the perfect opportunity for the Browns to prove themselves worthy of the optimism.
Pick : Browns 33, Ravens 28.
Chicago Bears at Detroit Lions (-3)
Sunday, 1 p.m. ET, Fox.
The Lions are getting a field goal at home, which basically makes this game a toss-up. The Bears recently announced Mitchell Trubisky won the starting quarterback job over Nick Foles, which probably matters very little to their Week 1 opponent. Detroit is simply focused on the return of its own QB and what that will do for an offense that was making strides before he got hurt last season.
Pick : Lions 27, Bears 17.
New York Jets at Buffalo Bills (-6 1/2)
Sunday, 1 p.m. ET, CBS.
After reaching the playoffs as a wild card last year, the Bills noticed what was happening around them in the AFC East and did everything they could to pad what was already a solid roster. They'll be good enough defensively to win their first division title since the Clinton administration, and they hope the addition of Stefon Diggs will be enough to lift Josh Allen to a Pro Bowl level. The Jets, meanwhile, are not yet ready to contend.
Pick : Bills 27, Jets 10.
Indianapolis Colts (-7 1/2) at Jacksonville Jaguars.
Sunday, 1 p.m. ET, CBS.
Philip Rivers now lives in Florida, not too far from where he will make his debut as the Colts' new quarterback. Indianapolis signed the veteran hoping his savvy will help get the team back to the playoffs a year after Andrew Luck's sudden retirement. While the Colts are in win-now mode, the Jaguars appear to be in . whatever the opposite of win-now mode is. This spread is big for good reasons.
Pick : Colts 31, Jaguars 13.
Las Vegas Raiders (-3) at Carolina Panthers.
Sunday, 1 p.m. ET, CBS.
We have absolutely no idea what to expect from the Panthers, a team with a new coaching staff, a new quarterback and an overhauled defense that no longer features Luke Kuechly. The Raiders can't know what to expect, either, which is why a team that flirted with the postseason last year is barely favored over a team that had no shot.
Pick : Raiders 27, Panthers 24.
Los Angeles Chargers (-3) at Cincinnati Bengals.
Sunday, 4:05 p.m. ET, CBS.
The Chargers are starting Tyrod Taylor over Justin Herbert at quarterback, so this will not be a matchup featuring QBs who were selected in the top six picks of the 2020 NFL Draft. If Joe Burrow comes out of the gate as well as the Bengals expect, though, a Chargers loss to open the season against last year's worst team might push them to think more about playing the rookie. The fact that Burrow no longer has to deal with the injured Derwin James in this game is notable.
Pick : Bengals 28, Chargers 21.
Tampa Bay Buccaneers at New Orleans Saints (-3 1/2)
Sunday, 4:25 p.m. ET, Fox.
This is Sunday's game of the day, if not the game of the week, thanks to Tom Brady's move from New England to Tampa Bay in free agency. The Buccaneers hype is real, and for good reason. This team flirted with the playoffs last year on the strength of an underrated defense despite seemingly endless turnovers from former passer Jameis Winston. Brady won't make the same mistakes, which gives Tampa Bay a legitimate chance to steal the division from New Orleans.
Pick : Buccaneers 30, Saints 27.
Arizona Cardinals at San Francisco 49ers (-7)
Sunday, 4:25 p.m. ET, Fox.
The Cardinals are excited about what the DeAndre Hopkins addition will mean for their offense around rising star quarterback Kyler Murray, and they should expect to win many more games than they did last year. Arizona probably is not yet on the level of San Francisco and Seattle in the division. That might not matter in Week 1, though, when the 49ers are so thin at wide receiver.
Pick : Cardinals 28, 49ers 27.
Dallas Cowboys (-3) at Los Angeles Rams.
Sunday, 8:20 p.m. ET, NBC.
This was supposed to be the grand opening for the brand-new SoFi Stadium in Los Angeles, and it technically still is even though there will be no fans in attendance. That crowd would have been cluttered with Cowboys fans, anyway, so the change might actually be advantageous for the Rams. Regardless, Dallas is the more loaded team.
Pick : Cowboys 23, Rams 20.
Pittsburgh Steelers (-5) at New York Giants.
Monday, 7:10 p.m. ET, ESPN.
This is a tricky spot for the Steelers, on the road to open the season in a strange "Monday Night Football" window. But Pittsburgh is back in contention mode with Ben Roethlisberger returning to the lineup and such a stingy defense ready to get the offensive support it deserves.
Pick : Steelers 26, Giants 14.
Tennessee Titans at Denver Broncos (-1 1/2)
Monday, 10:20 p.m. ET, ESPN.
The Titans are probably looking at this line and playing the disrespect card even though they're opening the season on the road in a weird time slot. We can't blame them, because even though their run to last season's AFC championship game came with a series of upsets, they're a legitimately solid team and much more proven than the Broncos. The disrespect card should work, at least for Week 1.

NFL odds, picks, predictions for Week 1, 2020: Advanced computer model loving Bears, 49ers.
SportsLine's computer model simulated every Week 1 NFL game 10,000 times with surprising results.
NFL odds are on the move as kickoffs approach. In Atlanta, the Falcons are one-point favorites over the Seahawks in the latest NFL spreads from William Hill after opening as one-point underdogs. In Carolina, the visiting Raiders opened as 1.5-point favorites, but the line has since doubled to a field goal. Wide receiver Kenny Golladay (hamstring) is inactive for the Lions, who are still 2.5-point favorites over the NFC North rival Bears in the latest NFL betting lines, up a point from the opener.
On Sunday Night Football, the Cowboys vs. Rams line opened at Dallas -2.5, but betting on L.A. has reduced the spread to -2. All of the Week 1 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 1 NFL picks now.
The SportsLine Projection Model simulates every NFL game 10,000 times and is up over $7,000 for $100 players on its top-rated NFL picks since its inception five years ago.
It also enters the 2020 NFL season on an incredible 96-65 roll on top-rated NFL picks that dates back to the 2017 season. The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.
Now, it has examined the latest Week 1 NFL odds and lines, simulated every snap, and its predictions are in. Head to SportsLine now to see them all.
Top NFL predictions for Week 1.
The Bears struggled offensively, but ranked fourth in the league in scoring defense in 2019 (18.6) in 2019. Chicago is also 5-2-1 against the spread in its last eight meetings against Detroit and on a 9-4 run against the spread versus NFC North foes. SportsLine's model says Chicago covers in over 50 percent of simulations, while the under (42) also brings plenty of value because that hits well over 60 percent of the time.
Another one of the Week 1 NFL picks from the model: The 49ers (-7) cover as home favorites against the Cardinals. Kyler Murray and the Cardinals look prepared to take a step forward in Year Two under Kliff Kingsbury, while the offseason addition of DeAndre Hopkins certainly adds to the allure. However, the 49ers' defense is simply too strong and San Francisco's rushing attack is a perfect compliment.
The 49ers ranked second in the NFL in total defense in 2019 and first against the pass. They allowed just 4.8 net yards per pass attempt thanks to the top defensive front in the league and an experienced and capable secondary led by Richard Sherman.
SportsLine's model predicts that Murray is sacked four times and the 49ers force two turnovers. San Francisco covers in well over 50 percent of simulations, while the under (48) also hits over half the time.
How to make Week 1 NFL picks.
The model also has a strong pick for Tom Brady's debut with the Buccaneers against the Saints, and is calling for a favored Super Bowl contender to go down hard in an upset this week. You can only get every pick for every game at SportsLine.
What NFL picks can you make with confidence in Week 1? And which Super Bowl contender goes down hard? Check out the latest NFL odds below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that is up over $7,000 on its top-rated NFL picks.

Week 1 NFL picks, predictions.
NFL picks and predictions are difficult enough in Week 1 of a given season when we know so little about how offseason roster changes will manifest on the field. Now we're picking NFL games to open a season defined by changes amid the COVID-19 pandemic. Welcome to 2020.
Only two of the 16 games on the Week 1 NFL schedule will feature fans in the stands, as the Chiefs and Jaguars will allow a small percentage of their stadiums' capacities to be filled. So the typical home-field advantage attached to the odds for each game is not as much of a factor.
However, team travel for away games during the coronavirus pandemic is extra stressful, so the teams scheduled to make lengthy trips in Week 1 will be the first to deal with the NFL's extensive health and safety protocols for teams on the road.
Per tradition, the Week 1 NFL schedule begins with the defending Super Bowl champions вЂ” this year the Chiefs вЂ” hosting the Thursday night season-opener, and it ends with a "Monday Night Football" doubleheader.
Here are our Week 1 NFL picks straight up, all the way through that pair of Monday night games.

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